Khoom

Tsev / Khoom/ Tshuaj Reagents / Organic Reagents

4-Hydroxyphenethyl Cawv

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Khoom Taw qhia

4-Hydroxyphenethyl cawv Cov ntaub ntawv yooj yim

Kev piav qhia Kev Noj Qab Haus Huv Cov Kev Pab Cuam Tshuam Kev Siv

Khoom npe:	4-Hydroxyphenethyl cawv
Synonyms:	4-Hydroxyphenyl-2-ethanol; Tyrosol (antioxidant): 4-(2-hydroxyethyl)phenol; P-HYDROXY PHENETHYL ALCOHOL; PHEP;2-({{6 }}Hydroxyphenyl) ethanol (p-HPEA); TYROSOL; Para Hydroxy Phenethyl Alcohol; Benzeneethanol, 4-hydroxy-
CAS:	501-94-0
MF:	C8H10O2
MW:	138.16
EINECS:	207-930-8
Khoom Categories:	Inhibitors; Aromatics; Benzhydrols, Benzyl & Special Alcohols; Benzene derivates; Intermediates & Fine Chemicals; Pharmaceuticals; Alcohols thiab Derivatives; Alkohols; API intermediates; Alcohols; Tsev Blocks; C7 rau C8; Tshuaj Synthesis; Europa; Olive); Organic Building Blocks; Oxygen Compounds; Phytochemicals by Plant (Food/Spice/Herb); chemical reagent; pharmaceutical intermediate; phytochemical; reference standard from suav tshuaj ntsuab (TCM); standardized herbal extract; bc0001;{{3} }
Mol File:	501-94-0.mol

4-Hydroxyphenethyl cawv Chemical Properties

Melting point	89-92 degree (lit.)
Boiling point	195 degree (18 mmHg)
ceev	1.0742 (zeeg)
Refractive Index	1.5590 (kwv yees)
Fp	139 degree / 1 hli
cia temp.	Khaws hauv qab +30 degree .
solubility	124g/l
pka ua	1 0.17 ± 0.13 (Tau)
daim ntawv	Crystalline hmoov los yog Crystalline hmoov
xim	Off-dawb rau lub teeb beige
tsw	ntawm 100.00%. me ntsis qab zib floral fruity
Hom tshuaj tsw qab	paj ntoo
Dej Solubility	me ntsis soluble
BRN	1859884
InChIKey	YCCILVSKPBXVIP-UHFFFAOYSA-N
LogP	0.851 (yog)
CAS DataBase Reference	501-94-0(CAS DataBase Reference)
NIST Chemistry Reference	Benzeneethanol, 4-hydroxy-(501-94-0)
EPA Tshuaj Registry System	4-Hydroxybenzeneethanol (501-94-0)

Cov ntaub ntawv kev nyab xeeb

Hazard Codes	Xis
Risk Statements	36/37/38
Cov lus hais txog kev nyab xeeb	26-37/39-24/25-36
WGK Germany	3
F	10
Ceeb toom	Irritant
TSCA	Yog lawm
HS Code	29072900

MSDS Cov Ntaub Ntawv

Tus kws kho mob	Lus
2-(4-Hydroxyphenyl) ethanol	Lus Askiv
SigmaAldrich	Lus Askiv
ACROS	Lus Askiv
ALFA	Lus Askiv

4-Hydroxyphenethyl cawv Siv Thiab Synthesis

Kev piav qhia	Phenylalanine yog ib qho amino acid, uas yog lub tsev thaiv cov proteins hauv koj lub cev. Cov molecule no muaj nyob rau hauv ob daim ntawv los yog kev npaj: L-phenylalanine thiab D-phenylalanine. Lawv yuav luag zoo tib yam tab sis muaj cov qauv molecular sib txawv me ntsis. L-form muaj nyob rau hauv cov zaub mov thiab siv los tsim cov proteins hauv koj lub cev, thaum D-form tuaj yeem tsim los siv rau hauv qee yam kev kho mob. Koj lub cev tsis tuaj yeem tsim L-phenylalanine txaus ntawm nws tus kheej, yog li nws tau suav tias yog ib qho tseem ceeb amino acid uas yuav tsum tau txais los ntawm koj cov khoom noj. Nws muaj nyob rau hauv ntau yam khoom noj - ob qho tib si cog thiab tsiaj. Ntxiv rau nws lub luag haujlwm hauv kev tsim cov protein ntau, phenylalanine yog siv los ua lwm cov molecules tseem ceeb hauv koj lub cev, ntau yam uas xa cov cim ntawm qhov sib txawv ntawm koj lub cev. Phenylalanine tau kawm raws li kev kho mob rau ntau yam mob, nrog rau kev mob ntawm daim tawv nqaij, kev nyuaj siab thiab mob. Txawm li cas los xij, nws tuaj yeem ua rau muaj kev phom sij rau cov neeg muaj kab mob caj ces phenylketonuria (PKU).
Cov txiaj ntsig kev noj qab haus huv	Phenylalanine tuaj yeem siv los tsim cov dopamine molecule. Dopamine malfunction nyob rau hauv lub hlwb yog txuam nrog qee hom kev nyuaj siab. Ib qho me me 12-tus neeg txoj kev tshawb fawb pom tau tias muaj txiaj ntsig zoo ntawm kev sib xyaw ntawm D- thiab L-cov ntaub ntawv ntawm cov amino acid no rau kev kho kev nyuaj siab, nrog 2/3 ntawm cov neeg mob qhia kev txhim kho . Txawm li cas los xij, muaj lwm yam kev txhawb nqa me me rau phenylalanine cov teebmeem ntawm kev nyuaj siab, thiab feem ntau cov kev tshawb fawb tsis tau pom cov txiaj ntsig meej. Ntxiv nrog rau vitiligo thiab kev nyuaj siab, phenylalanine tau kawm txog qhov muaj peev xwm cuam tshuam rau: Mob: D-form ntawm phenylalanine tuaj yeem ua rau mob nyem rau qee zaus, txawm tias kev tshawb fawb tau sib xyaw .Cawv tshem tawm: Ib qho me me ntawm kev tshawb fawb qhia tias qhov no amino acid, nrog rau lwm cov amino acids, tuaj yeem pab txo cov tsos mob ntawm kev haus cawv.Parkinson's disease: Cov pov thawj tsawg heev qhia tias phenylalanine tuaj yeem pab kho tus kab mob Parkinson, tab sis xav tau kev tshawb fawb ntxiv.ADHD: Tam sim no, kev tshawb fawb tsis qhia txog cov txiaj ntsig ntawm Qhov no amino acid rau kev kho mob ntawm kev puas siab puas ntsws hyperactivity disorder (ADHD).
Kev mob tshwm sim	Phenylalanine muaj nyob rau hauv ntau cov khoom noj uas muaj protein ntau thiab "feem ntau lees paub tias muaj kev nyab xeeb" los ntawm Food and Drug Administration (FDA) (27). Tus nqi ntawm cov amino acid no pom hauv cov zaub mov yuav tsum tsis txhob ua rau muaj kev pheej hmoo rau lwm tus neeg noj qab haus huv. Dab tsi ntxiv, feem ntau ob peb lossis tsis muaj kev phiv tshwm sim feem ntau pom ntawm koob tshuaj ntxiv ntawm 23–45 mg ib phaus (50–100 mg ib kg) ntawm lub cev hnyav (9Trusted Source, 13Trusted Source). Txawm li cas los xij, nws yuav yog qhov zoo tshaj rau cov poj niam cev xeeb tub kom tsis txhob noj cov tshuaj phenylalanine.
Siv	L-phenylalanine (LPA) ua lub tsev thaiv rau ntau yam proteins uas tsim tawm hauv lub cev. LPA tuaj yeem hloov mus rau L-tyrosine (lwm cov amino acid) thiab tom qab ntawd rau L-dopa, norepinephrine, thiab epinephrine. LPA kuj tuaj yeem hloov pauv (los ntawm txoj kev sib cais) mus rau phenylethylamine, ib yam khoom uas tshwm sim hauv lub hlwb thiab zoo li ua rau lub siab.
Chemical Properties	tawm-dawb mus rau lub teeb beige siv lead ua los yog crystalline
Siv	Phenolic antioxidant.
Siv	Tyrosol (Metoprolol EP Impurity G) yog phenolic antioxidant.
Txhais	ChEBI: Ib qho phenol hloov ntawm txoj hauj lwm 4 los ntawm 2- pawg hydroxyethyl.
Kev piav qhia dav dav	2-(4-Hydroxyphenyl) ethanol yog phenolic cawv feem ntau muaj nyob rau hauv cov dej khib nyiab ntawm txiv ntseej.
Biochem/physiol Actions	Antioxidant pom nyob rau hauv txiv roj roj.

4-Hydroxyphenethyl alcohol Preparation Products And Raw khoom

Cov khoom nyoos	Glyoxal-->4'-Hydroxyacetophenone
Cov khoom npaj	2-(4-BENZYLOXYPHENYL)ETHANOL-->4-[2-(CYCLOPROPYLMETHOXY)ETHYL]PHENOL-->2-(4-HYDROXYPHENYL)PROPIONIC ACID-->Methyl 4-hydroxyphenylacetate-->p-Cresol-->3-bromo-4-hydroxybenzeneethanol-->4-(2-FLUOROETHYL)PHENOL(WXFC0726)-->4-[2-[Methyl(2-phenylethyl)amino]ethyl]phenol-->4- -D-Glucopyranosyloxybenzeneethanol

Cim npe nrov: 4-hydroxyphenethyl cawv, Tuam Tshoj 4-hydroxyphenethyl cawv manufacturers, lwm tus neeg, Hoobkas

Tug: 1,2,{2}}Butanetriol

Tom ntej: Triethylene Glycol Monobenzyl Ether

Koj Tseem Yuav Zoo Li

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