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2-Fluoro-5-((3-oxoisobenzofuran-1(3H)-ylidene)methyl)benzonitrile

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2-Fluoro-5-((3-oxoisobenzofuran-1(3H)-ylidene)methyl)benzonitrile Cov ntaub ntawv tseem ceeb

Khoom npe:	2-Fluoro-5-((3-oxoisobenzofuran-1(3H)-ylidene)methyl)benzonitrile
Synonyms:	2-Fluoro-5-[(3-oxo-1(3H)-isobenzofuranylidene)methyl]-benzonitrile;(Z)-2-fluoro-5-( (3-oxoisobenzofuran-1(3H)-ylidene)Methyl)benzonitrile;2-fluoro-5-((3-oxoisobenzofuran-1(3H)- ylidene)Methyl)benzonitrile;2-Fluoro-5-(3-oxo-3H-isobenzofuran-1-}ylidenemethyl)-benzonitrile;2-fluoro{{ 27}}(3-oxo-1,3-dihydroisobenzofuranylidene methyl)benzonitrile;(E)-2-fluoro-5-((3-oxoisobenzofuran{{ 34}}(3H)-ylidene)methyl)benzonitrile;2-fluoro-5-[(Z)-(3-oxo-2-benzofuran-1-ylidene)methyl ]benzonitrile;Benzonitrile, 2-fluoro-5-[(3-oxo-1(3H)-isobenzofuranylidene)methyl]-
CAS:	763114-25-6
MF:	C16H8FNO2
MW:	265.24
EINECS:
Khoom Categories:	kev tiv thaiv; 1
Mol File:	763114-25-6.mol

2-Fluoro-5-((3-oxoisobenzofuran-1(3H)-ylidene)methyl)benzonitrile Cov Khoom Siv Tshuaj

Boiling point	43 0.1 ± 45.0 degree (Predicted)
ceev	1.38
cia temp.	Muab kaw rau hauv qhuav, Chav Kub
solubility	Dichloromethane, Tetrahydrofuran
daim ntawv	Khoom
xim	Dawb
InChI	InChI=1S/C16H8FNO2/c17-14-6-5-10(7-11(14)9-18)8-15-12-3-1-2-4-13(12)16(19)20-15/h 1-8H
InChIKey	MMPHWTMMVPBHRZ-UHFFFAOYSA-N
SMILES	C(#N)C1=CC(C=C2C3=C=CC=C3)C(=O) O2)=CC=C1F

Cov ntaub ntawv kev nyab xeeb

HS Code

2932990090

MSDS Cov Ntaub Ntawv

2-Fluoro-5-((3-oxoisobenzofuran-1(3H)-ylidene)methyl)benzonitrile Siv Thiab Synthesis

Chemical Properties	Dawb Khoom
Siv	2-Fluoro-5-[(3-oxo-1(3H)-isobenzofuranylidene)methyl]-benzonitrile yog nruab nrab hauv kev npaj ntawm poly (ADP-ribose) polymerase (PARP) inhibitors. Olaparib nruab nrab.
Synthesis	({{0}}oxo-1,3-dihydroisobenzofuran-1-yl)phosphonic acid (5.00 g, 0 { 19}}21 mol) hauv tetrahydrofuran (30 mL) tau ntxiv rau 150 mL puag ncig-hauv qab khob. Rau cov tshuaj no, triethylamine (5.6 mL, 0.042 mol) tau ntxiv. 2-Fluoro-5-formyl benzonitrile (3.08 g, 0.021 mol) tau yaj hauv tetrahydrofuran rau hauv lwm lub khob hauv qab, tom qab ntawd ntxiv triethylamine (2.9 mL, 0.021 mol) thiab nplawm tusyees. Tom qab ntawd cov tshuaj tiv thaiv cov kua dej hauv ob lub khob tau muab sib xyaw thiab ua rau hauv chav sov li 12 teev. Cov khoom yog concentrated nyob rau hauv lub siab txo thiab 50 mL dej ntxiv. Lub ncua kev kawm ntawv yog stirred rau 30 min kom txog thaum cov khib nyiab tsis precipitated. Thaum kawg, kev lim dej tau ua tiav, thiab cov ncuav qab zib lim tau sau thiab qhuav kom tau txais 2-Fluoro-5-[(3-oxo-1(3H)-isobenzofuranylidene)methyl]-benzonitrile (5.41 g, 97%).

2-Fluoro-5-((3-oxoisobenzofuran-1(3H)-ylidene)methyl)benzonitrile Kev Npaj Khoom Siv Thiab Cov Khoom Raw

Cov khoom nyoos	Benzonitrile, 5-ethenyl-2-fluoro--->3-oxo-1,3-dihydroisobenzofuran-1-ylphosphonic acid-->2-FLUORO-5-FORMYLBENZONITRILE
Cov khoom npaj	2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)Methyl)benzonitrile-->2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)Methyl)benzoic acid

Cim npe nrov: 2-fluoro-5-((3-oxoisobenzofuran-1(3h)-ylidene)methyl)benzonitrile, Tuam Tshoj 2-fluoro-5-(({{ 8}}oxoisobenzofuran-1(3h)-ylidene)methyl)benzonitrile manufacturers, lwm tus neeg, Hoobkas

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Tom ntej: 2-BROMO-2',5'-DIMETHOXYACETOPHENONE

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