Khoom Taw qhia
| Cov ntaub ntawv tseem ceeb ntawm Trimethoxymethane |
| Khoom npe: | Trimethoxymethane |
| Synonyms: | Orthoformicacidmethylester; Thrimethyl orthoformate; TrimethyL ORTHOFORMATE, ANHYDROUS, 99.8%; TrimethylOrthoFormate (Tmof); Trimethylorthoformate, 98+%; METHYLFORMIAT-ORTHO; 99.8% FORTHImethylor; |
| CAS: | 149-73-5 |
| MF: | C4H10O3 |
| MW: | 106.12 |
| EINECS: | 205-745-7 |
| Khoom Categories: | Organic synthesis; ncaj saw txuas; Orthoesters; 149-73-5 |
| Mol File: | 149-73-5.mol |
 |
|
| Trimethoxymethane Chemical Properties |
| Melting point | -53 degree |
| Boiling point | 101-102 degree (lit.) |
| ceev | 0.97 g/mL ntawm 25 degree (lit.) |
| vapor ceev | 3.67 (vs huab cua) |
| vapor siab | 23.5 hli Hg (20 degree) |
| Refractive Index | n20 / D 1.379 (lit.) |
| Fp | 60 degree F |
| cia temp. | Khaws hauv qab +30 degree . |
| solubility | Miscible nrog ether, cawv thiab benzene. |
| daim ntawv | Ua kua |
| xim | Ntshiab xim tsis muaj xim |
| tawg txwv | 1.4-44.6%(V) |
| Dej Solubility | 10 g / L (hydrolysis) |
| rhiab heev | Moisture Sensitive |
| Merck | 14,6884 |
| BRN | 969215 |
| InChIKey | PYOKUURKVVELLB-UHFFFAOYSA-N |
| LogP | -0 03-0.09 ntawm 20 degree |
| CAS DataBase Reference | 149-73-5(CAS DataBase Reference) |
| NIST Chemistry Reference | Methane, trimethoxy-(149-73-5) |
| EPA Tshuaj Registry System | Trimethoxymethane (149-73-5) |
| Cov ntaub ntawv kev nyab xeeb |
| Hazard Codes | F, Xis |
| Risk Statements | 11-36 |
| Cov lus hais txog kev nyab xeeb | 9-16-26-29 |
| RIDADR | UN 3272 3/PG 2 |
| WGK Germany | 1 |
| RTECS | RM6650000 |
| Autoignition Kub | 255 degree |
| TSCA | Yog lawm |
| HazardClass | 3 |
| PackingGroup | II |
| HS Code | 29159080 |
| Cov Ntaub Ntawv Muaj Xwm Ceev | 149-73-5(Cov ntaub ntawv muaj phom sij) |
| Toxicity | LD50 qhov ncauj hauv Luav: 3130 mg / kg |
| MSDS Cov Ntaub Ntawv |
| Tus kws kho mob | Lus |
|---|---|
| Methyl orthoformate | Lus Askiv |
| SigmaAldrich | Lus Askiv |
| ACROS | Lus Askiv |
| ALFA | Lus Askiv |
| Trimethoxymethane Siv Thiab Synthesis |
| Kev piav qhia | Trimethyl orthoformate yog ib qho hnyav hnyav rau thallium (III) nitrate-mediated oxidation. Nws tau txais cov tshuaj tiv thaiv acid catalyzed nrog 6-(ND-ribitylanilino) uracils los ua 8-demethyl-8-hydroxy-5-deazariboflavins. |
| Chemical Properties | Cov kua dej tsis muaj xim |
| Siv | Trimethyl orthoformate yog siv los ua cov pab pawg tiv thaiv aldehydes hauv cov organic synthesis, ua ib qho ntxiv hauv polyurethane txheej thiab ua tus neeg ua kom lub cev qhuav dej hauv kev npaj ntawm qhov chaw hloov kho colloidal silica nanoparticles. Nws kuj yog siv los ua tshuaj nruab nrab hauv kev npaj cov tshuaj vitamin B1 thiab sulfa. Nws ua raws li qhov hnyav hnyav rau thallium (III) nitrate-mediated oxidation. Tsis tas li ntawd. Nws yog siv rau cov synthesis ntawm chromone los ntawm keto-hydroxy naphthol nyob rau hauv lub xub ntiag ntawm trimethylamine. |
| Siv | Trimethyl Orthoformate yog qhov yooj yim tshaj plaws orthoester. Siv nyob rau hauv cov organic synthesis raws li ib tug reagent rau qhia ib pab pawg neeg tiv thaiv aldehydes thiab nyob rau hauv lub creation ntawm methoxymethylene pawg thiab heterocyclic nplhaib systems. |
| Siv | Trimethyl orthoformate tuaj yeem siv: Txhawm rau hloov sulfonic acids rau methyl esters. Txhawm rau hloov 2-acylcyclohexanones rau cov acetal derivatives. Txhawm rau kho Pinacol cov tshuaj tiv thaiv ntawm ntau yam 1,2-diols nrog tin (IV) chloride yam tsis muaj dej. Los ua ke 1-substituted-1H-1,2,3,4-tetrazoles ntawm peb lub ntsiab lus condensation nrog amine thiab sodium azide catalyzed los ntawm indium triflate nyob rau hauv hnyav-dawb tej yam kev mob. Rau qhovN-methylation ntawm amines nyob rau hauv lub xub ntiag ntawm sulfuric acid. |
| Daim ntawv thov | Trimethyl orthoformate tau siv los ua tus neeg sawv cev lub cev qhuav dej hauv kev npaj ntawm qhov chaw hloov kho colloidal silica nanoparticles. MOM tiv thaiv Diols siv Trimethyl Orthoformate N-Formylation ntawm Amino Acid Esters |
| Kev piav qhia dav dav | Trimethyl orthoformate yog ib qho hnyav hnyav rau thallium (III) nitrate-mediated oxidation. Nws tau txais cov tshuaj tiv thaiv acid catalyzed nrog 6-(N-D-ribitylanilino) uracils tsim 8-demethyl-8-hydroxy-5-deazariboflavins. |
| Flammability thiab Explosibility | Cov nplaim taws heev |
| Kev ruaj ntseg Profile | Ib daim tawv nqaij thiab qhov muag irritant. Qhov phom sij txaus ntshai heev thaum raug tshav kub lossis nplaim taws; tuaj yeem cuam tshuam nrog oxidizing cov ntaub ntawv. Txaus ntshai los npaj. Txhawm rau tua hluav taws, siv CO2, pos huab, haze. Thaum rhuab mus rau decomposition nws emissions pa luam yeeb thiab irritating fumes. Saib ESTERS thiab. |
| Synthesis | Trimethyl orthoformate yog npaj rau kev lag luam nplai los ntawm methanolysis ntawm hydrogen cyanide: HCN + 3 HOCH3 → HC(OCH3)3 + NH3 Trimethyl orthoformate kuj tuaj yeem npaj los ntawm cov tshuaj tiv thaiv ntawm chloroform thiab sodium methoxide, piv txwv ntawm Williamson ether synthesis. |
| Cov kev ceev faj | Moisture rhiab heev. Khaws lub thawv kaw kom nruj rau hauv qhov chaw qhuav thiab qhov cua zoo. Incompatible nrog acids thiab muaj zog oxidizing tus neeg sawv cev. |
| Cov ntaub ntawv | Kev tiv thaiv rau pawg Hydroxyl, suav nrog 1,2- thiab 1,3-Diols PGM Wuts, hauv Greene's Protective Groups in Organic Synthesis, 5th ed., ed. los ntawm PGM Wuts, John Wiley & Sons, Inc., Hoboken, New Jersey, 2014, Chap. 2, 17. Cov txheej txheem yooj yim rau kev sib xyaw ntawm N-Formyl Amino Acid Esters T. Chancellor, C. Morton, Synthesis 1994, 10, 1023. |
| Trimethoxymethane Kev Npaj Cov Khoom Siv Thiab Cov Khoom Raw |
| Cov khoom nyoos | Sodium hydroxide-->Sodium-->Chloroform |
| Cov khoom npaj | N-METHYL-P-ANISIDINE-->N-Boc-5,6,7,8-tetrahydro-3-methoxy-[1,2,4]triazolo[4,3-A]pyrazine ,98%-->6-BROMO-4-CHLOROQUINOLINE-->5,6-DIHYDRO-4-METHOXY-2H-PYRAN-->4,7-DIMETHOXY-1,10-PHENANTHROLINE, 97%-->4-TRIFLUOROMETHYL-N-METHYLANILINE 97-->3-METHOXY-N-METHYLANILINE-->6-bromoquinolin-4(3H)-one-->Pipemidic acid-->Methyl trifluoroacetate-->Methyl methanesulfonate-->Tetramethoxyethylene-->ETHYL 5-AMINO-1-PYRIDIN-2-YL-1H-PYRAZOLE-4-CARBOXYLATE-->Bromoform-->THEBAINE-->2-Methylundecanal dimethylacetal-->(-)-Dimethyl D-tartrate-->P-ANISALDEHYDE DIMETHYL ACETAL-->6,7-DIHYDRO-2-PHENYL-5H-PYRROLO[2,1-C]-1,2,4-TRIAZOLIUM CHLORIDE-->BASIC RED 12 |
Cim npe nrov: Tuam Tshoj trimethoxymethane manufacturers, lwm tus neeg, Hoobkas
Tom ntej: Calcium Disodium Edetate Dihydrate
Koj Tseem Yuav Zoo Li
Xa kev nug
