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2-Hydroxy-2-methylpropiophenone

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2-Hydroxy-2-methylpropiophenone Cov ntaub ntawv yooj yim

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Khoom npe:	2-Hydroxy-2-methylpropiophenone
Synonyms:	Photocure-1173;1-Phenyl-2-Hydroxy-2-Methyl-1-Propanone;2-Hydroxy-2-Methylpheny-Propane{{8} }ib;1-Propanone, 2-hydroxy-2-methyl-1-phenyl-; ACETOCURE 73;1-Phenyl-2-hydroxy-2- methylpropane{18}}ib qho;1-Phenyl-2-methyl-2-hydroxy-1-propanone;2-Hydroxy-2-methyl{25}} phenylpropane -1-ib
CAS:	7473-98-5
MF:	C10H12O2
MW:	164.2
EINECS:	231-272-0
Khoom Categories:	Lwm Cov Khoom Siv; Cov Khoom Siv Ua Haujlwm; Photopolymerization Initiators; Acetophenone; Organic Photoinitiators; Polymerization Initiators; Kev Lag Luam / Tshuaj Zoo; Ntxiv rau cov yas; Pharmaceutical Intermediates
Mol File:	7473-98-5.mol

2-Hydroxy-2-methylpropiophenone Chemical Properties

Melting point	4 degree
Boiling point	102-103 degree 4 mm Hg (lit.)
ceev	1.077 g / mL ntawm 25 degree (lit.)
vapor siab	0.57Pa ntawm 20 degree
Refractive Index	n20/D 1.533 (lit.)
Fp	>230 degree F
cia temp.	Khaws nyob rau hauv qhov chaw tsaus, kaw hauv qhuav, Chav Kub
solubility	Xyaum insoluble hauv dej
daim ntawv	kua ntshiab
pka ua	13.23 ± 0.29 (Tshaj tawm)
Specific Gravity	1.077
xim	Colorless to Light txiv kab ntxwv mus daj
Dej Solubility	13.3g / L ntawm 20 degree
InChIKey	XMLYCEVDHLAQEL-UHFFFAOYSA-N
LogP	1.62 ntawm 25 degree
CAS DataBase Reference	7473-98-5(CAS DataBase Reference)
EPA Tshuaj Registry System	1-Propanone, 2-hydroxy-2-methyl-1-phenyl- (7473-98-5)

Cov ntaub ntawv kev nyab xeeb

Hazard Codes	Xn
Risk Statements	22
Cov lus hais txog kev nyab xeeb	23-36/37/39
RIDADR	3082
WGK Germany	3
RTECS	TIAB SA 2977245
HazardClass	9
PackingGroup	III
HS Code	29144000

MSDS Cov Ntaub Ntawv

Tus kws kho mob	Lus
SigmaAldrich	Lus Askiv

2-Hydroxy-2-Methylpropiophenone Siv Thiab Synthesis

Siv	2-Hydroxy-2-methylpropiophenone yog ib qho photoinitiator. Ntxiv rau, 2-hydroxy-2-methylpropiophenone yog ib qho tseem ceeb organic intermediate (lub tsev thaiv) los tsim cov khoom hloov pauv propiophenone.
Chemical Properties	Yellowish ntshiab kua
Siv	2-Hydroxy-2-benzoylpropane tau siv los ua ib qho catalyst hauv real-time kinetic kawm ntawm laser-induced polymerization. Nws tseem yog photoinitiator.
Synthesis Reference (cov)	Tetrahedron Letters, 29, p. 4365 Ib., 1988DOI: 10.1016/S0040-4039(00)80496-7
Kev piav qhia dav dav	2-Hydroxy-2-methylpropiophenone yog ib tug radical photoinitiator (PI) molecule uas yuav siv tau nyob rau hauv crosslinking ntawm polymers los ntawm raug UV hluav taws xob. Nws tuaj yeem siv rau hauv kev tsim cov UV curable resins rau sab nrauv txheej txheej.
Hazard	Muaj tshuaj lom los ntawm kev noj tshuaj.
Flammability thiab Explosibility	Tsis cais
Synthesis	KBr hauv dej yog ntxiv rau kev daws ntawm {{0}}methyl-1-phenylpropane-1,2-diol hauv toluene. Tom qab ntawd, TEMPO ntxiv. Lub caij nplooj ntoos hlav reddish yog txias rau 0 degree. Ib 12% sodium hypochlorite tov yog ntxiv thaum tswj qhov kub thiab txias ntawm 5 degree lossis qis dua. Cov sib tov yog stirred rau 1 h ntawm 0-5 degree thiab ces sib cais rau 10 min. Sodium dithionite tov (tau los ntawm 30 g sodium dithionite (85%) thiab 400 ml dej) yog ntxiv rau cov organic theem thiab stirred ntawm 85 degree rau 1-2 h. Cov theem ntawm cov organic yog rov sib cais thiab concentrated (rotavap). Cov khoom nyoos yog tom qab ntawd raug rau cov khoom siv feem ntau distillation, yielding 2-Hydroxy-2-methylpropiophenone li roj tsis muaj xim.