Khoom Taw qhia
| 1-Tetralone Cov ntaub ntawv yooj yim |
| Khoom npe: | 1-Tetralone |
| Synonyms: | KETOTETRAHYDRONAPHTHALENE;A-TETRALONE;1,2,3,4-TETRAHYDRO-1-NAPHTHALENONE;1-TETRALONE;3,4-DIHYDRO-2H-NAPHTHALEN{{ 11}}IB; 3,4-DIHYDRO-1-(2H)NAPHTHALENONE;3,4-DIHYDRO-1(2H)-NAPHTHALENONE;ALPHA-TETRALONE |
| CAS: | 529-34-0 |
| MF: | C10H10O |
| MW: | 146.19 |
| EINECS: | 208-460-6 |
| Khoom Categories: | Bioactive Me Molecules; Lub Tsev Blocks; C10; Carbonyl Compounds; Cell Biology; Chemical Synthesis; PHARMACEUTICAL INTERMEDIATES; Ketones; Organic Building Blocks; T; Cardiovascular & Blood System Agents; Pharmaceutical; bc0001; 529-34-0 |
| Mol File: | 529-34-0.mol |
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| 1-Tetralone Chemical Properties |
| Melting point | 2-7 degree (lit.) |
| Boiling point | 113-116 degree 6 mm Hg (lit.) |
| ceev | 1.099 g / mL ntawm 25 degree (lit.) |
| Refractive Index | n20 / D 1.568 (lit.) |
| Fp | >230 degree F |
| cia temp. | 2-8 degree |
| solubility | Chloroform, Ethyl Acetate (me ntsis) |
| daim ntawv | Ua kua |
| xim | xim av |
| Dej Solubility | insoluble |
| BRN | 607374 |
| InChIKey | XHLHPRDBBAGVEG-UHFFFAOYSA-N |
| CAS DataBase Reference | 529-34-0(CAS DataBase Reference) |
| NIST Chemistry Reference | 1(2H)-Naphthalenone, 3,4-dihydro-(529-34-0) |
| EPA Tshuaj Registry System | 1,2,3,4-Tetrahydronaphthalen-1-ib (529-34-0) |
| Cov ntaub ntawv kev nyab xeeb |
| Hazard Codes | Xn |
| Risk Statements | 22-20/22-20/21/22 |
| Cov lus hais txog kev nyab xeeb | 23-24/25-36 |
| WGK Germany | 3 |
| RTECS | QK4375000 |
| TSCA | Yog lawm |
| HS Code | 29143900 |
| Cov Ntaub Ntawv Muaj Xwm Ceev | 529-34-0(Cov ntaub ntawv muaj phom sij) |
| Toxicity | LD50 qhov ncauj hauv luav: 810 mg/kg LD50 dermal Luav > 2200 mg/kg |
| MSDS Cov Ntaub Ntawv |
| Tus kws kho mob | Lus |
|---|---|
| 1-Tetralone | Lus Askiv |
| SigmaAldrich | Lus Askiv |
| ACROS | Lus Askiv |
| ALFA | Lus Askiv |
| 1-Tetralone Siv Thiab Synthesis |
| Chemical Properties | Ntshiab amber mus rau xim av oily kua |
| Siv | 1-Tetralone yog ib qho reagent siv nyob rau hauv cov synthesis ntawm amino-pyrazolopyridines nrog anti-NF-κB thiab pro-apoptotic muaj peev xwm. |
| Synthesis Reference (cov) | Tetrahedron Letters, 32, p. 4291 Ib., 1991DOI: 10.1016/S0040-4039(00)92151-8 |
| Txoj Kev Purification | Tshawb xyuas IR ua ntej. Purify -tetralone los ntawm dissolving 20mL hauv Et2O (200mL), ntxuav nrog H2O (100mL), 5% aqueous NaOH (100mL), H2O (100mL), 3% aqueous AcOH (100mL) ), 5% NaHCO3 (100mL) ces H2O (100mL) thiab qhuav txheej ethereal tshaj MgSO4. Lim, evaporate thiab fractionate cov residue los ntawm 6in Vigreux kem (p 11) nyob rau hauv kev txo qis kom muab cov roj tsis muaj xim (~17g) nrog b 90-91o/0.50.7mm. [Snyder & Werber Org Synth Coll Vol III 798 1955.] Nws kuj tau raug fractionated los ntawm 0.5meter packed kem nrog lub tsho rhuab nyob rau hauv reflux siv ib nrab tshem tawm lub taub hau. Nws muaj max 247.5 thiab 290nm (hexane). phenylhydrazone muaj m83o. Lub 2,4,{35}}trinitrophenylhydrazone muaj m 247.5-248o (los ntawm EtOH). [Olson & Bader Org Synth Coll Vol IV 898 1963, Beilstein 7 H 370, 7 III 1416, 7 IV 1015.] |
| 1-Tetralone Preparation Products Thiab Raw Materials |
| Cov khoom nyoos | Aluminum chloride-->Hydrogen fluoride-->Polyphosphoric acid-->Phosphorus pentoxide-->Tin tetrachloride-->Butyryl chloride-->Gamma Butyrolactone-->4-Phenylbutyric acid-->1,2,3,4-Tetrahydronaphthalene-->5-Ethyl-2-methylpyridine-->Chromic acetate-->1(2H)-Naphthalenone, 3,4-dihydro-, 2,2-dimethylhydrazone-->(4,4-Difluoro-3-buten-1-yl)benzene-->4-Phenylbutyryl chloride |
| Cov khoom npaj | (S)-(-)-1,2,3,4-Tetrahedro-naphthoic acid-->γ-Hydroxybutyrophenone-->7-Hydroxy-1-tetralone-->2,3-Dihydro-1,4-naphthoquinone-->(S)-(+)-1,2,3,4-Tetrahydro-1-naphthol |
Cim npe nrov: 1-tetralone, Tuam Tshoj 1-tetralon manufacturers, lwm tus neeg, Hoobkas
Tug: Protocatechualdehyde
Tom ntej: 6-Bromoveratraldehyde
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