| Chemical Properties |
HNUB NO RAU LIM DEJ CRYSTALLINE MASS |
| Siv |
Organic synthesis, abscission ntawm citrus txiv hmab txiv ntoo nyob rau hauv sau. |
| Siv |
Bromoacetic acid yog siv rau hauv cov organic synthesis thiab ua tus neeg sawv cev alkylating. Nws kuj tseem siv los ua biochemical rau kev tshawb fawb proteomics. Nws yog ib qho tseem ceeb raw khoom thiab nruab nrab siv nyob rau hauv cov organic synthesis, tshuaj, dyes thiab agrochemicals. |
| Siv |
Bromoacetic acid feem ntau yog siv rau covN-terminal bromoacylation ntawm resin khi peptides.
Nws kuj tseem siv tau:Yuav kom synthesize (Z) -2-(cyclooct-4-en-1-yloxy)acetic acid.
Los ua ke -bromo-phenylacetamide.
Txhawm rau hloov aromatic thiosemicarbazones rau thiazolylhydrazones.
|
| Kev piav qhia dav dav |
Aqueous daws. |
| Cua & Dej Reactions |
Dej soluble. |
| Reactivity Profile |
Carboxylic acids, xws li BROMOACETIC ACID, pub hydrogen ions yog tias muaj lub hauv paus los txais lawv. Lawv hnov zoo li no nrog txhua lub hauv paus, ob qho tib si organic (piv txwv li, amines) thiab inorganic. Lawv cov kev cuam tshuam nrog cov hauv paus, hu ua "neutralizations", yog nrog los ntawm kev hloov pauv ntawm cov cua sov ntau heev. Neutralization ntawm cov kua qaub thiab lub hauv paus tsim cov dej ntxiv rau ntsev. Carboxylic acids nrog rau los yog tsawg dua carbon atoms yog dawb los yog me ntsis soluble nyob rau hauv dej; cov uas muaj ntau tshaj 6 carbons yog me ntsis soluble hauv dej. Soluble carboxylic acid dissociate rau ib tug npaum li cas nyob rau hauv dej kom yield hydrogen ions. Yog li pH ntawm kev daws ntawm carboxylic acids tsawg dua 7.0. Ntau cov carboxylic acids insoluble react sai sai nrog cov tshuaj aqueous uas muaj cov tshuaj hauv paus thiab yaj raws li cov neutralization tsim cov ntsev soluble. Carboxylic acids nyob rau hauv aqueous tov thiab kua los yog molten carboxylic acids tuaj yeem hnov mob nrog cov hlau nquag los tsim cov roj hydrogen thiab cov ntsev hlau. Cov tshuaj tiv thaiv zoo li no tshwm sim hauv txoj cai rau cov khoom carboxylic acids ib yam nkaus, tab sis qeeb yog tias cov kua qaub tseem qhuav. Txawm tias "insoluble" carboxylic acids yuav nqus dej txaus los ntawm huab cua thiab yaj txaus hauv Bromoacetic acid kom corrode los yog yaj hlau, hlau, thiab txhuas qhov chaw thiab ntim. Carboxylic acids, zoo li lwm cov kua qaub, hnov mob nrog cyanide ntsev los tsim cov pa roj carbon dioxide. Cov tshuaj tiv thaiv qeeb qeeb rau qhuav, khoom carboxylic acids. Insoluble carboxylic acids hnov mob nrog cov kev daws teeb meem ntawm cyanide ua rau tso tawm cov pa roj carbon dioxide. Cov nplaim hluav taws kub thiab / lossis cov pa phem thiab cua sov yog tsim los ntawm cov tshuaj tiv thaiv ntawm carboxylic acids nrog diazo tebchaw, dithiocarbamates, isocyanates, mercaptans, nitrides, thiab sulfides. Carboxylic acids, tshwj xeeb tshaj yog nyob rau hauv aqueous tov, kuj reacts nrog sulfites, nitrites, thiosulfates (kom muab H2S thiab SO3), dithionites (SO2), los tsim hluav taws kub thiab / los yog tshuaj lom gases thiab cua sov. Lawv cov tshuaj tiv thaiv nrog carbonates thiab bicarbonates tsim cov roj tsis muaj teeb meem (carbon dioxide) tab sis tseem kub. Zoo li lwm cov organic tebchaw, carboxylic acids tuaj yeem oxidized los ntawm cov neeg ua haujlwm oxidizing muaj zog thiab txo qis los ntawm cov neeg ua haujlwm txo qis. Cov tshuaj tiv thaiv no ua kom sov. Muaj ntau yam khoom siv tau. Zoo li lwm cov kua qaub, carboxylic acids tuaj yeem pib cov tshuaj tiv thaiv polymerization; zoo li lwm cov acids, lawv feem ntau catalyze (nce tus nqi ntawm) tshuaj tiv thaiv. |
| Hazard |
Muaj zog irritant rau ntawm daim tawv nqaij thiab cov ntaub so ntswg. |
| Health Hazard |
TOXIC; nqus tau, noj los yog sib cuag (tawv nqaij, qhov muag) nrog vapors, plua plav lossis khoom yuav ua rau raug mob hnyav, kub hnyiab lossis tuag. Kev sib cuag nrog cov khoom molten yuav ua rau mob hnyav rau ntawm daim tawv nqaij thiab qhov muag. Cov tshuaj tiv thaiv nrog dej los yog huab cua noo yuav tso cov pa phem, corrosive lossis flammable gases. Cov tshuaj tiv thaiv nrog dej tuaj yeem ua kom muaj cua sov ntau uas yuav ua rau kom cov pa taws ntau ntxiv hauv huab cua. Hluav taws yuav ua rau khaus, corrosive thiab/los yog cov pa phem. Cov dej ntws los ntawm kev tswj hluav taws los yog cov dej dilution tuaj yeem ua rau corrosive thiab / los yog tshuaj lom thiab ua rau muaj kuab paug. |
| Hluav Taws Xob |
Cov khoom siv combustible: tuaj yeem hlawv tab sis tsis ignite yooj yim. Cov tshuaj yuav hnov mob nrog dej (qee qhov hnyav) tso cov nplaim taws, muaj kuab lom lossis corrosive gases thiab ntws tawm. Thaum cua sov, vapors tuaj yeem tsim cov khoom tawg nrog huab cua: sab hauv tsev, sab nraum zoov thiab cov kav dej phwj tuaj tawg. Feem ntau cov vapors hnyav dua li huab cua. Lawv yuav kis tau mus rau hauv av thiab sau rau hauv qhov chaw qis lossis qhov chaw kaw (sewers, hauv qab daus, tanks). Vapors tuaj yeem mus rau qhov chaw ntawm qhov hluav taws kub thiab rov qab flash. Kev sib cuag nrog cov hlau tuaj yeem hloov pauv cov pa hluav taws xob hydrogen. Cov thawv ntim khoom tuaj yeem tawg thaum cua sov lossis yog tias muaj dej paug. |
| Flammability thiab Explosibility |
Tsis yog nplaim taws |
| Kev ruaj ntseg Profile |
Tshuaj lom los ntawm kev noj tshuaj, intraperitoneal, thiab txoj hlab ntshav. Irritating thiab corrosive rau daim tawv nqaij thiab mucous daim nyias nyias. Cov ntaub ntawv hloov pauv tau tshaj tawm. Thaum rhuab mus rau decomposition nws emits cov pa phem ntawm Br-. Saib BROMIDES thiab. |
| Txoj kev Purification |
Crystallize bromoacetic acid los ntawm tsiaj ether (b 40-60o). Diethyl ether daws ntawm nws yog dhau los ntawm alumina kem, thiab ether yog evaporated ntawm chav tsev kub hauv qab lub tshuab nqus tsev. Nws yog qhov zoo tshaj plaws tau los ntawm distillation los ntawm Claisen (flask immersed nyob rau hauv ib tug roj da dej) haum nrog ib tug insulated Vigreux kem (p 11) thiab cov feem b 108-110o/30mm yog sau. Nws yog lub teeb thiab noo noo rhiab heev. [Natelson & Gottfried Org Synth Coll Vol III 381 1955, Beilstein 2 IV 526.] LACHRYMATORY thiab yog daim tawv nqaij IRRITANT. |
