Khoom Taw qhia
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| Khoom npe: | 1-Bromopropane |
| Synonyms: | 1-bromo-propan; 1-Brompropan; bromo propane; Bromopropane; 1, 3-Br-propane; 1-BROMOPROPANE, 99%1-BROMOPROPANE, 99% 1-BROMOPROPANE, 99%1-BROMOPROPANE, 99%;1-BroMopropane, 99% 250ML; Bromopropane, 1- |
| CAS: | 106-94-5 |
| MF: | C3H7 Ib |
| MW: | 122.99 |
| EINECS: | 203-445-0 |
| Khoom Categories: | Agrochemical Intermediates; Alkyl; Lub Tsev Blocks; Tshuaj Synthesis; Halogenated Hydrocarbons; Organic Lub Tsev Blocks; Organics; ALKYL BROMIDE; Alkyl Bromides; Monofunctional & alpha, omega-Bifunctional Alkanes; {{Monofunctional Alkanes; 1Quinolines; } };bc0001 |
| Mol File: | 106-94-5.mol |
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| 1-Bromopropane Chemical Properties |
| Melting point | -110 degree |
| Boiling point | 71 degree (lit.) |
| ceev | 1.354 g / mL ntawm 25 degree (lit.) |
| vapor ceev | 4.3 (vs huab cua) |
| vapor siab | 146 hli Hg (20 degree) |
| Refractive Index | n20/D 1.434 (lit.) |
| Fp | 72 degree F |
| cia temp. | Khaws hauv qab +30 degree . |
| solubility | Soluble hauv acetone, ethanol, ether, benzene, chloroform, carbon tetrachloride |
| daim ntawv | kua ntshiab |
| xim | Colorless mus Yuav luag tsis muaj xim |
| tawg txwv | 3.4-9.1%(V) |
| Dej Solubility | 2.5 g/L (20 ºC) |
| rhiab heev | Lub teeb Sensitive |
| Merck | 14,7845 |
| BRN | 505936 |
| Henry's Law Constant | 7.3 * 10-3 atm-m3/mol (kwv yees) |
| Kev txwv tsis pub dhau | ACGIH: TWA 0.1 ppm |
| Dielectric tsis tu ncua | 8.1 (25 degree) |
| Kev ruaj ntseg: | Stability Flammable - ceeb toom tsawg flash point. Incompatible nrog muaj zog oxidizing neeg sawv cev, muaj zog hauv paus. |
| LogP | 2.1 |
| CAS DataBase Reference | 106-94-5(CAS DataBase Reference) |
| NIST Chemistry Reference | Propane, 1-bromo-(106-94-5) |
| IARC | 2B (Vol. 115) 2018 |
| EPA Tshuaj Registry System | 1-Bromopropane (106-94-5) |
| Cov ntaub ntawv kev nyab xeeb |
| Hazard Codes | F,T |
| Risk Statements | 60-11-36/37/38-48/20-63-67 |
| Cov lus hais txog kev nyab xeeb | 53-45 |
| RIDADR | UN 2344 3/PG 2 |
| WGK Germany | 2 |
| RTECS | TX 411 000 |
| F | 8 |
| Autoignition Kub | 914 degree F |
| TSCA | Yog lawm |
| HazardClass | 3 |
| PackingGroup | II |
| HS Code | 29033036 |
| Cov Ntaub Ntawv Muaj Xwm Ceev | 106-94-5(Cov ntaub ntawv muaj phom sij) |
| Toxicity | LD50 qhov ncauj hauv luav: > 2000 mg/kg LD50 dermal Rat > 2000 mg/kg |
| MSDS Cov Ntaub Ntawv |
| Tus kws kho mob | Lus |
|---|---|
| 1-Bromopropane | Lus Askiv |
| SigmaAldrich | Lus Askiv |
| ACROS | Lus Askiv |
| ALFA | Lus Askiv |
| 1-Kev siv Bromopropane thiab Synthesis |
| Kev piav qhia | Bromopropane yog ib qho tshuaj lom thiab kub heev, tsis muaj xim; Flash point #22 degree. Molecular hnyav=123 0 (1-bromopropane); 123. 0 (2-bromopropane); boiling point =71 degree (1-bromopropane); 59.4 degree (2-bromopropane); Txias / Melting point =-110 degree (1-bromopropane); - 89 degree (2-bromopropane); Specificgravity (H2O:1): 1.35 ({{20}}bromopropane); Flash point =-10 degree (cc) (1-bromopropane); Autoignitiontemperature =490 degree ({24}}bromopropane). Explosive Limitsin huab cua: LEL=4.6%; UEL=tsis paub. HazardIdentification (raws li NFPA-704 M Rating System): (asn-propyl bromide): Health 2, Flammability 3, Reactivity0; (2-bromopropane) Kev Noj Qab Haus Huv 2, Flammability 3, Reactivity3. Soluble hauv dej; solubility =0.25% ntawm 20 degree (1-bromopropane). |
| Chemical Properties | 1-Bromopropane (1-BP), tseem hu ua n-propyl bromide, yog cov kua tsis muaj xim rau daj ntseg daj nrog lub zog, muaj ntxhiab tsw qab. Nws yog soluble hauv qee cov organic solvents thiab me ntsis soluble hauv dej. 1-BP yog cov kua nplaum nplaum uas muaj qhov kub ntawm 220 degree. Nws vapor kuj yog flammable. 1-Bromopropane yog ib qho hnyav uas siv rau hauv degreasing, qhuav tu, tshuaj tsuag adhesives, aerosol solvents thiab resins thiab feem ntau yog siv los ua tshuaj nruab nrab hauv kev tsim tshuaj tua kab, quaternary ammonium compounds, flavors thiab fragrances, thiab tshuaj nyob rau hauv kaw cov txheej txheem (NTP, 2013). Nyob rau hauv nruab nrab mus rau lig 1990s, 1-bromopropane tau qhia raws li ib tug uas tsis yog-tshuaj lom, ceev-drying hnyav uas tsis tawm ntawm nto residue rau ntxuav hlau, yas, thiab kho qhov muag, hluav taws xob thiab hluav taws xob Cheebtsam (NTP, 2011 ; NIOSH, 2013). Nws tau ua lag luam los ua cov kuab tshuaj hloov pauv rau ozone-depleting thiab lwm cov kuab tshuaj xws li trichloroethylene, tetrachlorethylene (perchloroethylene) thiab methylene chloride. 1-Bromopropane yog siv rau vapor degreasing thiab immersion tu, kua thiab tshuaj tsuag daim ntaub nplaum, ntaub qhuav tu, thiab cov tshuaj tsuag aerosol (Blando li al., 2010; NTP, 2013). |
| Siv | 1-bromopropane feem ntau yog siv los ua cov kuab tshuaj rau cov rog, waxes lossis resins thiab ua ib qho nruab nrab hauv kev sib txuas ntawm lwm cov tshuaj xws li tshuaj, tshuaj tua kab, quaternary ammonium compounds, flavors thiab fragrances nyob rau hauv feem ntau tswj tau zoo, kaw cov txheej txheem. 1-Tam sim no Bromopropane tau siv los ua cov kuab tshuaj ntxuav hauv vapor thiab immersion tu thiab degreasing kev ua haujlwm rau optics, electronics thiab hlau thiab ua cov kuab tshuaj hauv kev lag luam uas siv cov nplaum nplaum. Nws siv los ua ib qho hnyav hloov rau ozone-depleting chlorofluorohydrocarbons (freons) los yog xav tias carcinogens (xws li, trichloroethylene, methylene chloride) tau ua rau kev lag luam tu qhuav kom pom nws hloov pauv rau perchlorethylene ("perc"), tshwj xeeb tshaj yog nyob rau hauv cov xeev. thov kom txwv tsis pub siv cov tshuaj tom kawg hauv kev ntxuav kom qhuav. 1-Bromopropane yog ib qho ntawm ntau cov tshuaj muaj nyob rau hauv Lub Chaw Haujlwm Tiv Thaiv Ib Cheeb Tsam Qhov Tseem Ceeb Tshiab Lwm Txoj Cai (SNAP) uas tau pom zoo los ua ib qho kev hloov pauv rau cov kuab tshuaj ozone-depleting tam sim no siv hauv qee daim ntawv thov. Tshwj xeeb tshaj yog, 1-bromopropane tau raug pom zoo los ua ib qho kev hloov tau rau CFC-113 (1,1,2-Trichloro1,2,2-trifluoroethane, Freon 113) thiab methyl chloroform ( 1,1,1-trichloroethane) hauv cov khoom siv hluav taws xob uas tsis yog aerosol, hlau thiab precision tu. |
| Siv | 1-Bromopropane yog siv los ua cov kuab tshuaj rau cov nplaum, degreasing plastics thiab optics. Nws yog siv rau hauv kev tsim cov asphalt, hluavtaws fiber ntau thiab aerosols. Nws yog ua hauj lwm los ntxuav cov hlau nto, hluav taws xob Circuit Court boards, thiab multi-layered OLEDs (Organic Light Emitting Diodes). Nws ua haujlwm los hloov perchlorethylene ua cov tshuaj ntxuav kom qhuav. |
| Kev npaj | 1-Bromopropane tuaj yeem ua ke los ntawm kev ua haujlwm n-propyl cawv (n-propanol) nrog ntau tshaj hydrobromic acid. Cov dej tsim los ntawm cov khoom lag luam raug tshem tawm sai sai ntawm cov khoom lag luam crude ua ntej purification kom muab cov khoom kawg. Kev hloov kho ntawm cov txheej txheem tshuaj tiv thaiv no suav nrog kev siv bromine nrog cov tshuaj txo qis xws li sulfur, sulfur dioxide, phosphorus lossis sodium borohydride. Tag nrho cov tshuaj tiv thaiv nrog hydrobromic acid yog piav qhia hauv qab no. n-C3H7OH + HBr =>n-C3H7Br + H2O Cov lus ua ntej n (lossis ib txwm) yog hais txog "txoj saw ncaj" hydrocarbon tivthaiv tsis zoo rau cov khoom siv hydrocarbon, xws li pawg isopropyl hauv isopropyl cawv (i-propyl cawv lossis i-propanol) qhov twg pawg hydroxyl (−OH) yog txuas rau nruab nrab carbon. |
| Txhais | ChEBI: 1-bromopropane yog bromoalkane uas yog propane nqa bromo hloov pauv ntawm txoj haujlwm 1. Nws muaj lub luag haujlwm ua neurotoxin thiab hnyav. Nws yog bromoalkane thiab bromohydrocarbon. |
| Daim ntawv thov | 1-Bromopropane yog siv los ua ib feem ntawm ntau yam qauv ntawm binary mixs, npaj los kawm lawv cov khoom xws li viscosity thiab refractive index. Nws tuaj yeem siv ua alkylating reagent: Rau kev ua haujlwm ntawm seleno-substituted imidazo[1,2-]pyridine derivatives. Rau kev sib txuas ntawm 1, 4-dihydroxy-2-propoxy anthraquinone derivatives. Nws kuj tseem siv tau los ua ib qho reactant: Rau cov synthesis ntawm Berberine-benzimidazole derivatives. Rau cov synthesis ntawm alkyl aryl ketones ntawm carbonylative Barbier-Negishi coupling nrog aryl iodides. |
| Kev piav qhia dav dav | 1-bromopropane zoo li cov kua tsis muaj xim. Me ntsis denser dua dej thiab me ntsis soluble hauv dej. Flash point hauv qab 75 degree F. Thaum rhuab mus rau qhov kub siab tuaj yeem tawm cov pa phem. Kev phom sij tshwj xeeb ntawm Cov Khoom Siv Hluav Taws Xob: Cov pa phem ntawm Hydrogen Bromide (USCG, 1999) |
| Cua & Dej Reactions | Cov nplaim taws heev. Me ntsis soluble hauv dej. |
| Reactivity Profile | Halogenated aliphatic tebchaw, xws li 2-BROMOPROPANE, yog nruab nrab los yog heev reactive. Reactivity feem ntau txo nrog nce qib ntawm kev hloov ntawm halogen rau hydrogen atoms. Tsawg molecular hnyav haloalkanes yog cov nplaim taws heev thiab tuaj yeem hnov mob nrog qee cov hlau los tsim cov khoom txaus ntshai. Cov ntaub ntawv hauv pab pawg no tsis sib haum nrog muaj zog oxidizing thiab txo cov neeg ua haujlwm. Tsis tas li, lawv tsis sib haum nrog ntau cov amines, nitrides, azo / diazo tebchaw, alkali hlau, thiab epoxides. Emits cov pa phem ntawm bromine thaum hlawv. |
| Hazard | 1-Bromopropane raug cais raws li Qeb 2 cov kua nplaum nplaum. Nws muaj qhov kub thiab txias ntawm 914 ° F thiab qhov taw tes qis dua 72 ° F. Txawm hais tias tsis tau txiav txim siab qhov tshwj xeeb ntawm qhov tawg (flammable) txwv, nws muaj qhov txwv qis dua ntawm 4.6 feem pua ntawm qhov ntim hauv huab cua. 1-Bromopropane decomposes thaum hlawv kom emit hydrogen bromide (HBr) roj. |
| Health Hazard | Kev ua haujlwm raug rau 1-bromopropane feem ntau tshwm sim los ntawm kev nqus pa thiab sib chwv ntawm daim tawv nqaij, txawm hais tias kis tau los ntawm kev noj thiab qhov muag yog lwm txoj hauv kev. Lub sij hawm luv luv rau cov tshuaj tuaj yeem ua rau khaus ntawm qhov muag, qhov ntswg, caj pas lossis ua pa. Ntev ntev (ntev) raug rau 1-bromopropane tuaj yeem cuam tshuam rau cov hlab ntsha peripheral thiab lub hauv nruab nrab lub paj hlwb. Cov tsos mob uas tau tshaj tawm muaj xws li mob pob qij txha lossis ceg tsis muaj zog thiab mob ua rau nyuaj rau sawv thiab taug kev; nqaij ntshiv los yog loog loog, tingling thiab prickling nyob rau hauv ob txhais tes los yog ob txhais taw, poob ntawm kev co kev xav; thiab ntxhov siab vim, apathy, insomnia, thiab teeb meem nrog concentration thiab nco. Lwm yam teebmeem kev noj qab haus huv uas tseem tuaj yeem tshwm sim muaj xws li dermatitis, xeev siab thiab ntuav, raws plab, nyuaj rau nqos, cuam tshuam los yog tsis ua raws li kev coj khaub ncaws, urinary nyuaj, anemia lossis hematocrit qis (cov ntshav liab suav), siab puas, thiab mob ntsws. |
| Flammability thiab Explosibility | Cov nplaim taws heev |
| Kev ruaj ntseg Profile | Mob hnyav heev los ntawm kev noj cov tshuaj thiab intraperitoneal txoj kev. Mob me me los ntawm kev nqus pa. Kev sim ua kom muaj menyuam. Cov ntaub ntawv hloov pauv tau tshaj tawm. Kev phom sij phom sij thaum kub los yog raug nplaim taws lossis oxidizers. Txhawm rau tua hluav taws, siv dej, ua npuas ncauj, CO2, tshuaj qhuav. Thaum rhuab mus rau decomposition nws emits cov pa phem ntawm Br-. Saib BROMIDES thiab. |
| Ntxim yuav nphav raug | Tumorigen; Reproductive Effector. Siv los ua lwm yam tshuaj. |
| Kev pab thawj zaug | Yog hais tias cov tshuaj no nkag mus rau hauv lub qhov muag, tshem tawm ib qho kev sib cuag lo ntsiab muag ib zaug thiab irrigate tam sim ntawd rau tsawg kawg yog 15 feeb, qee zaus nqa lub hau sab sauv thiab qis dua. Nrhiav kev kho mob tam sim ntawd. Yog tias cov tshuaj no kis rau ntawm daim tawv nqaij, tshem tawm cov khaub ncaws tsis huv thiab ntxuav tam sim nrog xab npum thiab dej. Nrhiav kev kho mob tam sim ntawd. Yog tias cov tshuaj no tau nqus tau lawm, tshem tawm ntawm qhov raug, pib ua pa cawm siav (siv kev ceev faj thoob ntiaj teb, suav nrog daim npog qhov ncauj resuscitation) yog tias ua pa tau nres thiab CPR yog tias lub plawv nres. Hloov tam sim ntawd mus rau qhov chaw kho mob. Thaum cov tshuaj no tau nqos lawm, mus ntsib kws kho mob. Muab dej ntau thiab ua kom ntuav. Tsis txhob ua rau tus neeg tsis nco qab ntuav. |
| khaws cia | Xim Code-Red: Flammability Hazard: Khaws rau hauv qhov chaw cia cov kua hluav taws xob los yog lub txee tso cai kom deb ntawm qhov hluav taws kub thiab cov khoom siv corrosive thiab reactive. Tiv thaiv kev puas tsuaj rau lub cev. Sab nraum lossis cais cia yog nyiam. Ua ntej ua haujlwm nrog Bromopropane koj yuav tsum tau kawm txog nws txoj kev tuav thiab khaws cia. Khaws cov thawv kaw kom nruj rau hauv qhov chaw txias, qhov cua zoo kom deb ntawm cov khoom siv tsis sib xws hauv qab no. Cov thawv hlau uas cuam tshuam txog kev hloov pauv ntawm cov tshuaj no yuav tsum tau muab tso ua ke thiab sib koom ua ke. Drums yuav tsum tau nruab nrog lub qhov rooj kaw qhov rooj, lub tshuab nqus tsev siab, thiab cov nplaim taws.Siv cov cuab yeej thiab cov khoom siv tsis muaj pa taws, tshwj xeeb tshaj yog thaum qhib thiab kaw cov ntim ntawm cov tshuaj no. Qhov chaw ntawm qhov hluav taws kub, xws li haus luam yeeb thiab qhib nplaim taws, yog txwv tsis pub nyob qhov twg cov tshuaj no siv, tuav, los yog khaws cia nyob rau hauv ib tug yam ntxwv uas yuav ua rau muaj hluav taws kub los yog tawg txaus ntshai. |
| Kev xa khoom | 2-Bromopropane yuav tsum muaj "FLAMMABLELIQUID" daim ntawv lo. Nws ntog hauv Hazard Class 3, PackingGroup II. |
| Txoj Kev Purification | Tej yam kab mob muaj xws li n-propyl cawv thiab isopropyl bromide. Cov txheej txheem purification yooj yim tshaj plaws yog siv ziab nrog MgSO4 lossis CaCl2 (nrog lossis tsis muaj kev ntxuav ua ntej ntawm bromide nrog aqueous NaHCO3, tom qab ntawd dej), tom qab ntawd los ntawm fractional distillation deb ntawm lub teeb ci. Chien thiab Willard [J Am Chem Soc 79 4872 1957] bubbed ib kwj ntawm oxygen uas muaj 5% ozone los ntawm n-propyl bromide rau 1 teev, ces co nws nrog 3% hydrogen peroxide tov, neutralized nws nrog aqueous Na2CO3, ntxuav nws nrog distilled dej thiab qhuav nws. Qhov no tau ua raws li kev sib xyaw ua ke nrog 95% H2SO4 kom txog thaum cov kua qaub tshiab tsis muaj xim tsis pub dhau 12 teev. Cov propyl bromide tau sib cais, nruab nrab, ntxuav, qhuav nrog MgSO4 thiab fractionally distilled. Qhov chaw txiav tau muab khaws cia rau hauv qhov tsaus ntuj. Hloov chaw ozone, Schuler thiab McCauley [J Am Chem Soc 79 821 1957] ntxiv bromine thiab khaws cia rau 4 lub lis piam, bromine ces muab rho tawm nrog aqueous NaHSO3 ua ntej kev kho sulfuric acid thiab thaum kawg distilled. Kev lim dej ntxiv yog los ntawm kev npaj roj chromatography ntawm ib kem ntim nrog 30% SE-30 (General Electric ethylsilicone roj hmab) ntawm 42/60 Chromosorb P ntawm 150o thiab 40psi, siv helium. [Chu J Phys Chem 41 226 1964, Beilstein 1 IV 205.] |
| Kev tsis sib haum xeeb | Muaj zog oxidants; lub hauv paus muaj zog |
| 1-Bromopropane Kev Npaj Cov Khoom Siv Thiab Cov Khoom Raw |
| Cov khoom nyoos | Sodium carbonate-->Sodium sulfate-->Hydrogen bromide-->Phosphorus-->1-Propanol |
| Cov khoom npaj | Albendazole-->Gemfibrozil-->1-Propanethiol-->Profenofos-->Ethoprophos-->4-(Propylthio)benzene-1,2-diamine-->SULPROFOS-->Prothiofos-->Pretilachlor-->1-N-PROPYLPIPERAZINE DIHYDROBROMIDE-->Oxibendazole-->DOXEPIN-->Ropivacaine-->3-Chloro-1-(N,N-dimethyl)propylamine-->Propylphosphonic anhydride-->Verapamil-->Probenecid-->O,O-diethyl-S-propyl dithiophosphate-->Diethyl dipropylmalonate-->4-(3-CHLOROPROPYL)-1-PIPERAZINE ETHANOL-->PROPYLTHIOSULFATE-->Propyl sulfide |
Cim npe nrov: 1-bromopropane, Tuam Tshoj 1-bromopropane manufacturers, lwm tus neeg, Hoobkas
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