Khoom Taw qhia
| Cov ntaub ntawv tseem ceeb ntawm Veratraldehyde |
| Chemical Properties Daim Ntawv Thov Kev Npaj |
| Khoom npe: | Veratraldehyde |
| Synonyms: | N-VERATRALDEHYDE ntshiab; Vanillin methyl ether, Veratraldehyde; Methyl vanilline; Vanilline methyl ether; 3, 4-Dimethoxybenzald; Extracts ntawm Veratrum aldehyde; 3, 4-DiMethoxybenzene carbenzide; {{4-Dimethoxybenzalde; |
| CAS: | 120-14-9 |
| MF: | C9H10O3 |
| MW: | 166.17 |
| EINECS: | 204-373-2 |
| Khoom Categories: | Isoquinolines, Quinolines, Quinaldines; API Intermediate; aldehyde Flavor; Aromatics; Lwm yam Reagents; Pharmaceutical intermediate; Pharmaceutical Raw Materials; FINE Chemical & INTERMEDIATES; Aromatic Aldehydes & Derivatives; 0de; {1}} |
| Mol File: | 120-14-9.mol |
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| Veratraldehyde Chemical Properties |
| Melting point | 40-43 degree (lit.) |
| Boiling point | 281 degree (lit.) |
| ceev | 1.1708 (zeeg) |
| vapor siab | 0.09Pa ntawm 24 degree |
| Refractive Index | 1.5260 (kwv yees) |
| FEMA | 3109|VERATRALDEHYDE |
| Fp | >230 degree F |
| cia temp. | 2-8 degree |
| solubility | cawv: dawb soluble |
| daim ntawv | Lumps los yog Fused Solid |
| Specific Gravity | 1.15 (kwv yees) |
| xim | Dawb rau daj |
| tsw | ntawm 10.00 % hauv dipropylene glycol. qab zib woody vanilla |
| Hom tshuaj tsw qab | creamy |
| Dej Solubility | <0.1 g/100 mL at 22 ºC |
| rhiab heev | Huab cua Sensitive |
| JECFA Number | 877 |
| Merck | 14,9951 |
| BRN | 473899 |
| Kev ruaj ntseg: | ruaj khov. Incompatible nrog cov hauv paus muaj zog, muaj zog oxidizing tus neeg sawv cev. |
| LogP | 0.8 ntawm 25 degree |
| CAS DataBase Reference | 120-14-9(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzaldehyde, 3, 4-dimethoxy-(120-14-9) |
| EPA Tshuaj Registry System | Veratraldehyde (120-14-9) |
| Cov ntaub ntawv kev nyab xeeb |
| Hazard Codes | Xn, xis |
| Risk Statements | 22-38-36/37/38-36/38 |
| Cov lus hais txog kev nyab xeeb | 26-22-24/25-36 |
| WGK Germany | 3 |
| RTECS | YX5088000 |
| F | 9-23 |
| TSCA | Yog lawm |
| HS Code | 29124900 |
| Toxicity | LD50 qhov ncauj hauv luav: 2000 mg/kg LD50 dermal Luav > 5000 mg/kg |
| MSDS Cov Ntaub Ntawv |
| Tus kws kho mob | Lus |
|---|---|
| 3, 4-Dimethoxy-benzaldehyde | Lus Askiv |
| SigmaAldrich | Lus Askiv |
| ACROS | Lus Askiv |
| ALFA | Lus Askiv |
| Veratraldehyde Siv thiab Synthesis |
| Cov khoom siv tshuaj | Dawb mus rau xim av los yog xiav-grey koob siv lead ua (crystallization hauv ether); qab zib woody tshuaj tsw qab, tsw qab nyom aroma thiab muaj zog tsw ntawm vanilla xiav; oxidized rau hauv odorless 3, 4-dimethoxybenzoic acid (veratric acid) nyob rau hauv cov huab cua; Melting point 43 ~ 45 degree; Insoluble hauv dej txias; soluble hauv dej kub, ethanol thiab roj. Cov khoom ntuj tsim muaj nyob rau hauv Java citronella roj thiab Hu Xanthium parsley roj thiab lwm yam. Siv GB 2760 a 1996 cov kev cai rau kev siv cov txuj lom zaub mov. |
| Daim ntawv thov |
Cov khoom no yog nruab nrab ntawm cov organic synthesis. Hauv kev lag luam kws tshuaj, nws yog siv los tsim cov tshuaj methamphetamine thiab tseem siv los tsim cov tshuaj tua tsiaj sulfonamide synergist. Ntxiv 0.02% (qhov hnyav) ntawm cov tshuaj tua tsiaj no tuaj yeem ua rau muaj txiaj ntsig zoo ntawm cov tshuaj iodine synergistic ntxiv hauv pub, uas tuaj yeem tiv thaiv thiab tswj cov kab mob nqaij qaib. Siv raws li kws tshuaj intermediate thiab tsuas yog siv rau tshuaj tua kab mob synthesis. |
| Kev npaj | Nws tuaj yeem muab tau los ntawm cov tshuaj tiv thaiv ntawm 3-methoxy-4-hydroxybenzaldehyde (vanillin) thiab dimethyl sulfate, los yog muab los ntawm methylation ntawm dimethyl sulfate nrog vanillin nyob rau hauv alkaline tej yam kev mob. |
| Chemical Properties | tawm-dawb crystalline khoom |
| Chemical Properties | Veratraldehyde yog crystalline khoom (mp 44.5-45 degree) nrog ib tug ntoo, vanilla zoo li tsw. Veratraldehyde tuaj yeem npaj tau los ntawm methylation ntawm vanillin. Nws yog siv nyob rau hauv oriental thiab sov, woody fragrances, raws li zoo raws li nyob rau hauv tsw compositions rau vanilla sau ntawv. Nws yog ib qho nruab nrab hauv, piv txwv li, cov synthesis ntawm pharmaceuticals. |
| Chemical Properties | Veratraldehyde muaj qab zib heev, woody, zoo li vanilla tsw nrog sov, qab zib, zoo li vanilla saj. Cov tshuaj no tau txais oxidized hauv huab cua kom tsis muaj ntxhiab veratric acid. |
| Qhov tshwm sim | Tshaj tawm ntawm cov ntsiab lus ntawm cov roj tseem ceeb ntawm Cymbopogon javanensis thiab Eryngium poterium. Kuj tseem pom muaj nyob rau hauv raspberry, qhiav, peppermint roj, Bourbon vanilla thiab mastic pos hniav roj. |
| Siv | Veratraldehyde tau siv rau hauv kev npaj ntawm 4-chloromethyl-2-(dimethoxyphenyl)-1, 3-dioxolane. Nws tau siv rau hauv kev sib txuas ntawm (+)-lithospermic acid, muaj kev tiv thaiv kab mob HIV. Nws tsim 1: 1 suav nrog complexes nrog cyclodextrins. Nws reacts nrog 3-acetyl-2, 5-dimethythiophene los tawm los chalcone dye, (2E)-3-(3,4-Dimethoxyphenyl)-1-( 2,5-dimethylthiophen-3-yl)prop-2-en-1-ib. |
| Kev npaj | Npaj los ntawm vanillin los ntawm methylation ntawm vanillin nrog dimethylsulfate nyob rau hauv me ntsis alkaline tej yam kev mob. |
| Txhais | ChEBI: Veratraldehyde yog dimethoxybenzene uas yog benzaldehyde hloov los ntawm methoxy pawg ntawm txoj hauj lwm 3 thiab 4. Nws muaj nyob rau hauv peppermint, qhiav, raspberry, thiab lwm yam txiv hmab txiv ntoo. Nws muaj lub luag haujlwm ua tus neeg sawv cev antifungal. Nws yog ib tug tswv cuab ntawm benzaldehydes thiab dimethoxybenzene. |
| Aroma pib qhov tseem ceeb | Cov yam ntxwv aroma ntawm 1.0%: phenolic, qab zib vanilla, hmoov, me ntsis ntoo nrog cov khoom qab zib thiab cocoa creaminess. |
| Saj pib qhov tseem ceeb | Cov yam ntxwv saj ntawm 50 ppm: phenolic, vanilla, qab zib hmoov cocoa, creamy, cherry zoo li nrog phenolic thiab balsamic nuances. |
| Synthesis Reference (cov) | Phau ntawv Journal of the American Chemical Society, 69, p. 2070 Ib., 1947DOI:10.1021/j01200a517 Organic Syntheses, Coll. Vol. 2 ib,p. 619 Ib., 1943 Tetrahedron Letters, 20, p. 975 Ib., 1979 |
| Kev piav qhia dav dav | Koob los yog chunky light peach hmoov. Nws muaj ib tug tsw ntawm vanilla taum. |
| Cua & Dej Reactions | Insoluble hauv dej. |
| Reactivity Profile | Veratraldehyde yog incompatible nrog muaj zog oxidizing neeg sawv cev thiab muaj zog puag. . Veratraldehyde yog aldehyde. Aldehydes tau nkag siab oxidized los muab carboxylic acids. Cov nplaim hluav taws kub thiab / lossis cov pa phem yog tsim los ntawm kev sib xyaw ntawm aldehydes nrog azo, diazo tebchaw, dithiocarbamates, nitrides, thiab muaj zog txo cov neeg ua haujlwm. Aldehydes tuaj yeem cuam tshuam nrog huab cua los muab thawj peroxo acids, thiab thaum kawg carboxylic acids. Cov tshuaj autoxidation no tau qhib los ntawm lub teeb, catalyzed los ntawm cov ntsev ntawm cov hlau hloov pauv, thiab yog autocatalytic (catalyzed los ntawm cov khoom ntawm cov tshuaj tiv thaiv). |
| Hluav Taws Xob | Veratraldehyde tej zaum combustible. |
| Flammability thiab Explosibility | Tsis cais |
| Biochem/physiol Actions | Saj ntawm 50 ppm |
| Txoj Kev Purification | Crystallize ether los ntawm diethyl ether, tsiaj ether, CCl4 los yog toluene. [Beilstein 8 IV 1765.] |
| Veratraldehyde Kev Npaj Cov Khoom Siv Thiab Cov Khoom Raw |
| Cov khoom nyoos | Dimethyl sulfate-->Vanillin |
| Cov khoom npaj | 3,4-Dihydroxyphenylacetic acid-->(3,4-Dimethoxyphenyl)acetic acid-->3,4-Dimethoxybenzyl alcohol-->3-PHENYLUMBELLIFERONE-->Methyldopa-->Diaveridine-->7-Hydroxy-6-methoxy-3,4-dihydroisoquinoline-->Fenoldopam-->3,4-Dimethoxyphenylacetone-->B-(3,4-DIMETHOXYPHENYL)-A-CYANOPROPIONALDEHYDE DIMETHYLACETAL-->6,7-Dimethoxy-2,4-Quinazolinedione-->SINENSETIN-->2,6-Bis-(3,4-Dimethoxyphenylmethylene)-Cyclohexanone |
Cim npe nrov: Tuam Tshoj veratraldehyde manufacturers, lwm tus neeg, Hoobkas
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