
Khoom Taw qhia
| Cuminaldehyde Cov ntaub ntawv yooj yim |
| Khoom npe: | Cuminaldehyde |
| Synonyms: | 4-(1-methylethyl)-benzaldehyd;4-(1-Methylethyl)benzaldehyde;4-(1-methylethyl)-Benzaldehyde; FEMA 2341; ISOPROPYLBENZALDEHYDE;LABOTEST-BB LT00933375;4-ISOPROPYLBENZALDEHYDE;4-CUMINOL |
| CAS: | 122-03-2 |
| MF: | C10H12O |
| MW: | 148.2 |
| EINECS: | 204-516-9 |
| Khoom Categories: | Aromatic Aldehydes & Derivatives (hloov); Benzene derivatives; bc0001 |
| Mol File: | 122-03-2.mol |
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| Cuminaldehyde Chemical Properties |
| Melting point | 97 degree |
| Boiling point | 235-236 degree (lit.) |
| ceev | 0.977 g/mL ntawm 25 degree (lit.) |
| Refractive Index | n20/D 1.529 (lit.) |
| FEMA | 2341|CUMINALDEHYDE |
| Fp | 200 degree F |
| cia temp. | Inert cua, 2-8 degree |
| solubility | ethanol: soluble 1mL / 4ML, ntshiab, tsis muaj xim (70%) |
| daim ntawv | Ua kua |
| xim | Ntshiab xim tsis muaj xim rau daj |
| tsw | ntawm 10.00 % hauv dipropylene glycol. ntsim cumin ntsuab tshuaj ntsuab |
| Hom tshuaj tsw qab | ntsim |
| Dej Solubility | insoluble |
| rhiab heev | Huab cua Sensitive |
| JECFA Number | 868 |
| Merck | 14,2621 |
| BRN | 636547 |
| Dielectric tsis tu ncua | 11. 0(15 degree) |
| LogP | 3.17 |
| CAS DataBase Reference | 122-03-2(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzaldehyde, 4-(1-methylethyl)-(122-03-2) |
| EPA Tshuaj Registry System | Cuminaldehyde (122-03-2) |
| Cov ntaub ntawv kev nyab xeeb |
| Hazard Codes | Xn, xis |
| Risk Statements | 22-36/37/38 |
| Cov lus hais txog kev nyab xeeb | 26-36-37/39 |
| WGK Germany | 2 |
| RTECS | UA 7000000 |
| TSCA | Yog lawm |
| HS Code | 29122900 |
| Toxicity | LD50 qhov ncauj hauv nas: 1390 mg / kg (Jenner) |
| MSDS Cov Ntaub Ntawv |
| Tus kws kho mob | Lus |
|---|---|
| 4-Isopropylbenzaldehyde | Lus Askiv |
| ACROS | Lus Askiv |
| SigmaAldrich | Lus Askiv |
| ALFA | Lus Askiv |
| Cuminaldehyde Siv thiab Synthesis |
| Chemical Properties | clear colorless mus yellow kua |
| Chemical Properties | Cuminaldehyde muaj zog, pungent, cumin zoo li tsw thiab saj zoo sib xws. |
| Qhov tshwm sim | Tshaj tawm hauv ntau cov roj yam tseem ceeb, cumin, Acacia farnesiana, cinnamon, iab txiv kab ntxwv, Mexican txiv qaub, Eucalyptus globulus, rue, boldus, Artemisia hausiliensis thiab lwm yam. Tsis tas li ntawd qhia nyob rau hauv txiv qaub thiab mandarin tev roj, cinnamon bark, anise, clove bud, cumin noob, turmeric, parsley, calabash nutmeg (Monodora myristica Dunal), angelica paus, thyme, nqaij nyuj, brandy, txiv hmab txiv ntoo thiab mastic gum txiv hmab txiv ntoo roj. |
| Siv | Cuminaldehyde yog ib qho tshuaj tsw qab uas yog kua, tsis muaj xim rau daj nyob rau hauv tsos, nrog ib tug muaj zog pungent tsw zoo li cumin roj. Nws yog insoluble hauv dej thiab soluble hauv cawv thiab ether. Nws yog tau los ntawm cumin roj. Nws tseem hu ua p-, cumaldehyde, thiab cuminal. |
| Siv | Cuminaldehyde tau siv los kawm txog larvicidal thiab adulticidal toxicity ntawm monoterpenes tawm tsamCulex pib. Nws tau siv nyob rau hauv kev ntsuam xyuas ntawm cov tshuaj muaj pes tsawg leeg, antimicrobial thiab antioxidant kev ua ub no ntawm cov roj yam tseem ceeb thiab ntau yam extracts ntawmEucalyptus gilii. |
| Txhais | ChEBI: Ib tug tswv cuab ntawm cov chav kawm ntawm benzaldehydes uas yog benzaldehyde hloov los ntawm ib pawg isopropyl ntawm txoj hauj lwm 4. Nws yog ib feem ntawm cov roj yam tseem ceeb los ntawm Cumin thiab nthuav tawm cov kab mob tua kab mob. |
| Kev npaj | Los ntawm p-isopropylbenzyl chloride thiab hexamethylenetetramine (Arctander, 1969). |
| Saj pib qhov tseem ceeb | Cov yam ntxwv saj ntawm 10 ppm: ntsim nrog ntsuab cumin thiab tshuaj ntsuab nuances. |
| Kev piav qhia dav dav | Cuminaldehyde yog ib qho tseem ceeb ntawm cov roj cumin uas pom muaj zog tiv thaiv kab mob thiab cov kab mob tua kab mob. |
| Biochem/physiol Actions | Cuminaldehyde nce cov insulin secretion hauv streptozotocin-induced ntshav qab zib nas. Nws inhibits melanin tsim nyob rau hauv kab lis kev cai murine B16-F10 melanoma hlwb. |
| Kev ruaj ntseg Profile | Muaj tshuaj lom los ntawm kev noj tshuaj thiab kev sib cuag ntawm daim tawv nqaij. Ib daim tawv nqaij irritant. Combustible kua. Thaum rhuab mus rau decomposition nws emissions pa luam yeeb thiab irritating fumes. Saib ALDEHYDES thiab. |
| Synthesis | Npaj synthetically los ntawm cua sov p-isopropyl benzoyl chloride nrog ib tug aqueous los yog cawv hexamethylenetetraamine tov. |
| Txoj Kev Purification | Qhov zoo tshaj plaws impurity yog benzoic acid. Tshawb xyuas IR kom pom muaj OH los ntawm CO2H, thiab CO zaus. Yog hais tias cov kua qaub tam sim no, ces yaj cov aldehyde hauv Et2O, ntxuav nws nrog 10% NaHCO3 kom txog thaum effervescence tas, ces nrog brine, qhuav dhau CaCl2, evaporate thiab distil cov roj seem, nyiam dua nyob rau hauv lub tshuab nqus tsev. Nws yuav luag insoluble hauv H2O, tab sis soluble hauv EtOH thiab Et2O. thiosemicarbazone muaj m147o tom qab recrystallisation los ntawm aqueous EtOH, MeOH los yog * C6H6. [Crounse J Am Chem Soc 71 1263 1949, Bernstein et al. J Am Chem Soc 73 906 1951, Gensler & Berman J Am Chem Soc 80 4949 1958, Beilstein 7 H 318, 7 II 347, 7 III 1095, 7 IV 723.] |
| Cuminaldehyde Kev Npaj Cov Khoom Siv Thiab Cov Khoom Raw |
| Cov khoom nyoos | Hexamethylenetetramine-->p-Cymene-->[acetyloxy-(4-propan-2-ylphenyl)methyl] acetate-->Benzene, 1-(1-methylethyl)-4-[[(trimethylsilyl)oxy]methyl]--->2-PROPYLZINC BROMIDE SOLUTION 0.5M IN T&-->4-ISO-PROPYL STYRENE-->4-ISOPROPYLBENZYLAMINE-->4-ISOPROPYLBENZYL CHLORIDE-->4-ISOPROPYLBENZYL ALCOHOL-->4-Bromobenzaldehyde-->Cumene |
| Cov khoom npaj | cyclamen aldehyde-->4-ISOPROPYL BENZYL BROMIDE 97-->1-(2-HYDROXYPHENYL)-3-(4-ISOPROPYLPHENYL)PROP-2-EN-1-ONE-->4-isopropylbenzaldehyde semicarbazone |
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