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4-Methylmorpholine N-oxide

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4-Methylmorpholine N-oxide Cov ntaub ntawv yooj yim

Khoom npe:	4-Methylmorpholine N-oxide
Synonyms:	4-methyl-morpholin4-oxide; Morpholine, 4-methyl-, 4-oxide; Morpholine, 4-methyl-, 4-oxide; N -Methylmorpholine oxide; N-METHYLMORPHOLINE 4-OXIDE; NMO;4-METHYLMORPHOLINE N-OXIDE;4-METHYLMORPHOLINE 4-OXIDE
CAS:	7529-22-8
MF:	C5H11NO2
MW:	117.15
EINECS:	231-391-8
Khoom Categories:	Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals; Heterocycles; Aromatic Morpholines; Oxidation; Synthetic Organic Chemistry; bc0001; 7529-22-8
Mol File:	7529-22-8.mol

4-Methylmorpholine N-oxide Chemical Properties

Melting point	180-184 degree (lit.)
Boiling point	118-119 degree
ceev	1.14 g / cm3³
vapor siab	1.41hPa ntawm 20 degree
Refractive Index	n20/D 1.43
Fp	118-119 degree
cia temp.	2-8 degree
solubility	DMSO (Soluble), Methanol (me ntsis)
daim ntawv	Ua kua
pka ua	4.93 ± 0.20 (Tshaj tawm)
xim	Ntshiab xim tsis muaj xim rau daj
PH	9. 00 (nyob zoo)
Dej Solubility	Soluble hauv dej, methanol, ethanol, acetone, ethers thiab dimethylsulfoxide.
BRN	507437
Kev ruaj ntseg:	Hygroscopic
LogP	-1.2 ntawm 25 degree
CAS DataBase Reference	7529-22-8(CAS DataBase Reference)
NIST Chemistry Reference	N-Methylmorpholine-N-oxide (7529-22-8)
EPA Tshuaj Registry System	Morpholine, 4-methyl-, 4-oxide (7529-22-8)

Cov ntaub ntawv kev nyab xeeb

Hazard Codes	Xis
Risk Statements	36/37/38
Cov lus hais txog kev nyab xeeb	26-36/37
WGK Germany	1
TSCA	Yog lawm
HS Code	29349990

MSDS Cov Ntaub Ntawv

Tus kws kho mob	Lus
4-Methylmorpholine N-oxide	Lus Askiv
SigmaAldrich	Lus Askiv
ALFA	Lus Askiv

4-Methylmorpholine N-oxide Siv Thiab Synthesis

Chemical Properties	Ntshiab xim tsis muaj xim rau daj
Siv	4-Methylmorpholine N-Oxide yog ib qho metabolite ntawm Morpholine (M723725). N-Methylmorpholine N-Oxide feem ntau yog siv los ua kom yaj cellulose zoo li hauv kev sib cais ntawm scleroproteins.
Siv	4-Methylmorpholine N-oxide ua raws li cov khoom siv tsis yog xim hlau rau cyanosilylation ntawm ketones. Nws kuj tseem ua haujlwm ua co-oxidant rau Sharpless asymmetric dihydroxylation hauv ionic kua. Nws ua hauj lwm raws li cov kuab tshuaj nyob rau hauv cov txheej txheem Lyocell los tsim tencel fiber. Tsis tas li ntawd, nws yog siv nyob rau hauv kev npaj ntawm aldehydes los ntawm thawj alcohols nyob rau hauv lub xub ntiag ntawm tetrapropylammonium perruthenate.
Siv	Non-metallic catalyst rau cyanosilylation ntawm ketones. Co-oxidant rau Sharpless asymmetric dihydroxylation hauv ionic kua.
Txhais	ChEBI: N-methylmorpholine N-oxide yog morpholine N-oxide tshwm sim los ntawm oxidation ntawm cov amino pawg N-methylmorpholine.
Kev piav qhia dav dav	4-Methylmorpholine?N-oxide yog ib qho organic compound siv los ua co-oxidant nrog rau OsO₄thiab ruthenates hauv organic synthesis. Hauv cov kev tshawb fawb tsis ntev los no, nws tau siv los ua ib qho catalyst hauv silylcyanation ntawm aldehydes thiab ketones. Lyocell, ib qho cellulose fiber ntau, tuaj yeem npaj siv 4-methylmorpholine?N- oxide nyob rau hauv eco-phooj ywg.
Flammability thiab Explosibility	Flamable
Txoj Kev Purification	Thaum cov oxide qhuav rau 2-3 teev ntawm lub tshuab nqus tsev siab, nws dehydrates. Ntxiv MeOH rau cov oxide thiab distil tawm cov kuab tshuaj nyob rau hauv lub tshuab nqus tsev kom txog rau thaum kub yog ca 95o. Tom qab ntawd ntxiv Me2CO ntawm reflux thiab txias rau 20o. Cov muaju yog lim tawm, ntxuav nrog Me2CO thiab qhuav. Qhov degree ntawm hydration yuav txawv thiab tej zaum yuav yog ib qho tseem ceeb rau cov kev xav tau. [van Rheenan et al. Tetrahedron Lett 1973 1076, Schneider & Hanze US Pat 2 769 823; saib kuj Sharpless et al. Tetrahedron Lett 2503 1976.]

4-Methylmorpholine N-oxide Npaj Cov Khoom Siv Thiab Cov Khoom Raw

Cov khoom npaj

4-METHYL-2-OXO-2 H-CHROMENE-7-CARBALDEHYDE-->N-Boc-4-oxo-L-Proline methyl ester-->4-Methylmorpholine N-oxide monohydrate-->4-Bromo-2-nitroaniline-->N,N'-Dimorpholinomethane-->BOC-4-OXO-L-PROLINE TERT-BUTYL ESTER-->PREGNANEDIONE

Cim npe nrov: 4-methylmorpholine n-oxide, Tuam Tshoj 4-methylmorpholine n-oxide manufacturers, lwm tus neeg, Hoobkas

Tug: Cyclamen Aldehyde

Tom ntej: Diethyl Malonate

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