Khoom Taw qhia
| 2',5'-Dihydroxyacetophenone Cov ntaub ntawv yooj yim |
| Khoom npe: | 2',5'-Dihydroxyacetophenone |
| Synonyms: | 1-(2,5-dihydroxyphenyl)-ethanon;1-Acetyl-2,5-dihydroxybenzene;2,5-Dihydroxy-1- acetylbenzene; 2',5'-dihydroxy-acetophenon; Acetophenone, 2',5'-dihydroxy-; Acetylhydroquinone; QUINACETOPHENONE; 2-Acetylhydroquinone Quinacetophenone |
| CAS: | 490-78-8 |
| MF: | C8H8O3 |
| MW: | 152.15 |
| EINECS: | 207-716-4 |
| Khoom Categories: | Tsev Blocks; C7 txog C8; Carbonyl Compounds; Tshuaj Synthesis; Ketones; Organic Building Blocks; FINE Tshuaj & INTERMEDIATES; Aromatic Acetophenones & Derivatives (hloov) |
| Mol File: | 490-78-8.mol |
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| 2',5'-Dihydroxyacetophenone Cov Khoom Siv Tshuaj |
| Melting point | 204-206 degree (lit.) |
| Boiling point | 234.6 degree (kev kwv yees ntxhib) |
| ceev | 1.2143 (kev kwv yees kwv yees) |
| Refractive Index | 1.4447 (kwv yees) |
| cia temp. | Khaws hauv qab +30 degree . |
| solubility | Dioxane: 50 mg / ml, ntshiab |
| pka ua | 9.86±{2}}.18 |
| daim ntawv | Crystalline hmoov los yog Crystalline hmoov |
| xim | Daj mus rau daj-ntsuab |
| Dej Solubility | insoluble |
| BRN | 637903 |
| InChIKey | WLDWSGZHNBANIO-UHFFFAOYSA-N |
| LogP | 1.274 (yeem) |
| CAS DataBase Reference | 490-78-8(CAS DataBase Reference) |
| NIST Chemistry Reference | Ethanone, 1-(2, 5-dihydroxyphenyl)-(490-78-8) |
| EPA Tshuaj Registry System | Ethanone, 1-(2, 5-dihydroxyphenyl)- (490-78-8) |
| Cov ntaub ntawv kev nyab xeeb |
| Hazard Codes | Xis |
| Risk Statements | 36/37/38 |
| Cov lus hais txog kev nyab xeeb | 26-36 |
| WGK Germany | 3 |
| RTECS | 770 000 AM |
| Ceeb toom | Irritant |
| TSCA | Yog lawm |
| HS Code | 29145000 |
| MSDS Cov Ntaub Ntawv |
| Tus kws kho mob | Lus |
|---|---|
| 2-Acetylhydroquinone | Lus Askiv |
| ACROS | Lus Askiv |
| SigmaAldrich | Lus Askiv |
| ALFA | Lus Askiv |
| 2',5'-Dihydroxyacetophenone Siv Thiab Synthesis |
| Kev piav qhia | 2',5'-Dihydroxyacetophenone yog lub ntuj phenolic compound uas muaj nyob hauv ntau cov nroj tsuag. Nws tau pom tias muaj cov tshuaj tiv thaiv kab mob los ntawm nws lub peev xwm los tiv thaiv kev tsim cov cytokines pro-inflammatory, xws li qog necrosis factor alpha thiab interleukin 1 beta. |
| Chemical Properties | daj mus rau daj-ntsuab crystals los yog |
| Siv | 2',5'-Dihydroxyacetophenone yog ib qho nruab nrab siv nyob rau hauv ntau yam khoom siv hluavtaws ntawm cov khoom muag, 1-(2,5-Dihydroxyphenyl) ethanone mus txog rau hauv kev sib txuas ntawm cov tshiab flavonoid fatty acid esters nrog anti-adipogenic thiab kev noj qab haus huv ntxiv cov dej num. |
| Siv | 1-(2,5-Dihydroxyphenyl)ethanone yog ib qho nruab nrab siv nyob rau hauv ntau yam khoom siv hluavtaws ntawm cov khoom siv tshuaj, 1-(2,5-Dihydroxyphenyl) ethanone tau mus txog rau hauv kev sib xyaw ntawm tshiab flavonoid fatty acid esters nrog anti-adipogenic thiab qabzib noj kev ua ub no. |
| Daim ntawv thov | 2',5'-Dihydroxyacetophenone inhibits qhov tsim ntawm reactive oxygen hom thiab nitric oxide nyob rau hauv nas neutrophils. Nws kuj muaj peev xwm txo oxidative kev nyuaj siab los ntawm kev tshem tawm cov dawb radicals thiab inhibiting lipid peroxidation. Lub hauv paus txheej txheem rau cov teebmeem no tsis to taub tag nrho tab sis yuav yog vim nws lub peev xwm los ua lub substrate rau matrix-pab laser desorption ionization (MALDI). Qhov no txhais tau hais tias nws muaj peev xwm hnov mob nrog protocatechuic acid molecules uas muaj nyob rau hauv cov qauv npaj chamber, ua rau polymerase saw cov tshuaj tiv thaiv (PCR) amplification. |
| Txhais | ChEBI: 2',5'-Dihydroxyacetophenone yog ib qho tshuaj tsw qab ketone. |
| Kev npaj | Kev npaj los ntawm Fries rearrangement ntawm hydroquinone diacetate, nrog aluminium chloride (91%) (76%) (63–77%) (55–60%) nrog zinc chloride hauv refluxing acetic acid (quantitative yield) nrog boron trifluoride etherate hauv benzene ntawm reflux (65%). |
| Synthesis Reference (cov) | Phau ntawv Journal of Organic Chemistry, 18, p. 1709, 1953 ibDOI:10.1021/jo50018a014 |
| 2',5'-Dihydroxyacetophenone Kev Npaj Cov Khoom Siv Thiab Cov Khoom Raw |
| Cov khoom nyoos | Aluminium chloride hexahydrate-->1, 4-Diacetoxybenzene |
| Cov khoom npaj | 3,6-DIHYDROXYFLAVONE-->6-Hydroxy-4-oxo-4H-1-benzopyran-2-carboxylic acid ethyl ester |
Cim npe nrov: 2',5'-dihydroxyacetophenone, Tuam Tshoj 2',5'-dihydroxyacetophenone manufacturers, lwm tus neeg, Hoobkas
Tom ntej: 2',5'-Dichloroacetophenone
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