| 4-fluoro-2-Methoxy-5-nitroaniline Cov ntaub ntawv yooj yim |
| Khoom npe: |
4-fluoro-2-Methoxy-5-nitroaniline |
| Synonyms: |
4-fluoro-2-Methoxy-5-nitroaniline;2-Amino-5-fluoro-4-nitroanisole, 4-Fluoro-5-nitro -o-anisidine;4-Fluoro-2-Methoxy-5-nitrobenzenaMine;4-Fluoro-2-methoxy-5-nitroaniline 95+%; Benzenamine , 4-fluoro-2-methoxy-5-nitro-;4-fluoro-2-methoxy-5-nitrophenylamine; AZD9291 intermediates; uoro-2-methoxy -5-nitroaniL |
| CAS: |
1075705-01-9 |
| MF: |
C7H7FN2O3 |
| MW: |
186.14 |
| EINECS: |
806-172-0 |
| Khoom Categories: |
AZD9291; API; 1075705-01-9 |
| Mol File: |
1075705-01-9.mol |
 |
| |
| 4-fluoro-2-Methoxy-5-Nitroaniline Chemical Properties |
| Melting point |
130 degree |
| Boiling point |
354.8 ± 37. 0 degree (Predicted) |
| ceev |
1.412 ± 0.06 g / cm3 (Tshaj tawm) |
| cia temp. |
nyob rau hauv inert gas (nitrogen los yog Argon) ntawm 2-8 degree |
| pka ua |
2.31 ± 0.10 (Tshaj tawm) |
| daim ntawv |
hmoov rau siv lead ua |
| xim |
Lub teeb daj rau xim av |
| InChI |
InChI=1S/C7H7FN2O3/c1-13-7-2-4(8)6(10(11)12)3-5(7)9/h2-3H,9H2,1H3 |
| InChIKey |
FYSIGSQCZXQTIH-UHFFFAOYSA-N |
| SMILES |
C1(N)=CC([N+]([O-])=O)=C(F)C=C1OC |
| |
| Cov ntaub ntawv kev nyab xeeb |
| |
| 4-fluoro-2-Methoxy-5-Nitroaniline Siv Thiab Synthesis |
| Siv |
4-Fluoro-2-methoxy-5-nitroaniline yog siv los ua reagent los npaj cov tshuaj tiv thaiv kab mob Mereletinib. |
| Synthesis |
{{0}}FLUORO-2-METHOXYANILINE (551 mg, 3.90 mmol) yog yaj hauv dichloromethane (39.0 mL), concentrated sulfuric acid (1.85 mL) yog ntxiv dropwise nrog nplawm hauv qab dej khov, thiab ces concentrated nitric acid (267 μL, 5.85 mmol) yog ntxiv dropwise. Tom qab nplawm rau 3 teev nyob rau hauv dej khov-txias, saturated aqueous sodium bicarbonate tau ntxiv kom txog rau thaum pH 8. Tom qab ntxuav nrog saturated aqueous sodium bicarbonate tov, ntxuav nrog saturated brine, cov organic txheej tau qhuav dhau sodium sulfate thiab evaporated nyob rau hauv txo siab kom tau 675 mg ntawm cov 4-fluoro-2-Methoxy-5- nitroaniline (yield 93%).
|
| |
| 4-fluoro-2-Methoxy-5-Nitroaniline Kev Npaj Khoom Thiab Raw Khoom |
| Cov khoom npaj |
N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine-->TIAB SA 7550 |
Tag:4-fluoro-2-Methoxy-5-nitroaniline(1075705-01-9)Related Product Information1,4-BenzenediaMine, N1-[2-(diMethylaMino)ethyl]-5-Methoxy-N1-Methyl-N4-[ 4-(1-Methyl-1H-indol-3-yl)-2-pyriMidinyl]{15}}nitro- 1-({17} }(3-Methoxy-4-nitrophenyl)piperidin-4-yl)-4-Methylpiperazine (2-((2,{24}}Dichloropyrimidin-4-) yl) amino) phenyl) dimethylphosphine oxide
Cim npe nrov: 4-fluoro-2-methoxy-5-nitroaniline, Tuam Tshoj 4-fluoro-2-methoxy-5-nitroaniline manufacturers, lwm tus neeg, Hoobkas
![2-Amino-5,8-dimethoxy-[1,2,4]triazolo[1,5-c]pyrimidine](/uploads/41226/small/2-amino-5-8-dimethoxy-1-2-4-triazolo-1-5-c2de79.gif?size=336x0)
